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Materials Science at Oregon State University

Bioactive Glasses as Restorative Materials for the Body: Bone Tissue Engineering and Dental Applications

Date: Thursday, Feb 17th
Presenter: John Mitchell, Associate Professor, Division of Biomaterials and Biomechanics in the Restorative Dentistry Department at OHSU School of Dentistry, Oregon Health and Sciences University

Abstract


This talk will focus on over a decade of investigations into the use of amorphous materials known collectively as Bioactive Glasses. These materials hold the promise to assist the body in regenerating damaged tissues by serving as a degradable physical scaffold that additionally releases chemical signals to encourage the body to heal itself. These materials have been tested for use alone as bone augmentation graft materials and cytokine carriers, and more recently as constituents within polymeric materials that can buffer the toxicity, pH changes, and loss of strength that are inherent in polymer degradation within the body.

Bio:
Dr. John C. Mitchell is an Associate Professor in the Division of Biomaterials and Biomechanics in the Restorative Dentistry Department at OHSU School of Dentistry. He holds a Joint appointment in the Department of Biomedical Engineering. Dr. Mitchell graduated from The Ohio State University, with a PhD in the dual majors of Implant Biomaterials Science and Tissue Engineering. He worked in both industry and academia before moving to OHSU in 2001, and has received numerous grants and awards, including the 2006 Innovation in Oral Health Care Award, 2009 Oregon Biosciences Innovation Award, and the 2010 Sigma Xi Outstanding Faculty Researcher Award. Dr. Mitchell’s research interests lie principally in the development of novel materials for hard tissue repair and regeneration. He is currently funded by two NIH grants to develop novel materials that will interact with the body’s own self healing mechanisms to repair and/or regenerate damaged tissues.