Date: Thursday, Nov 29th
Presenter: Prof. Victoria DeRose, Chemistry Department, University of Oregon
Electron paramagnetic resonance (EPR) spectroscopy detects unpaired spins in any type of material and has a rich history of applications towards materials, organic and inorganic chemistry, biosciences, and nearly any process involving movement of electrons. Newer applications of pulsed EPR spectroscopy provide nanoscale distance measurements between doped or endogenous spins, allowing structure information on the nanometer-Angstrom scale. EPR spectroscopy applied to distance measurements and to characterize transition metals in the heterogeneous environment of an RNA biopolymer provides examples of techniques that can be applied to many types of materials. These include site identification of doped Mn(II) ions based on ESEEM (electron spin echo envelope modulation) and ENDOR (electron-nuclear double resonance spectroscopy) measurements of hyperfine couplings, and interspin distances of 15-40 Angstroms from attached spin labels measured using DEER (double electron-electron resonance). An overview of new EPR and sensitive solid-state NMR instrumentation at the University of Oregon CAMCOR facilities will be provided.
Victoria DeRose is a Professor of Chemistry at the University of Oregon. She obtained a B.A. at the University of Chicago and a Ph.D. at the University of California-Berkeley, and was a postdoctoral researcher at Northwestern University. She was an Assistant and Associate Professor of Chemistry at Texas A and M University from 1995-2005 before moving to Oregon in 2006. She is a member of ONAMI, the UO Materials Sciences Institute, and the Institute of Molecular Biology, and is currently Acting Department Head of the UO Department of Chemistry. She is a Fellow of the AAAS.